Systemic Muscle Loss As a Consequence of Breast Radiotherapy

A comparison of contralateral breast dose due to breast cancer radiotherapy using two different treatment machines in a radiotherapy center

Background: The radiation dose received by contralateral breast (CLB) is one of the concerns of breast radiotherapy, because it may lead to the induction of secondary breast cancer. The aim of this study was to evaluate the CLB surface dose in the breast treatment in Yazd radiotherapy center. Materials and Methods: The surface dose of CLB was measured using TLD dosimetry in 50 cancer breast pat...

Arm Lymphedema as a Consequence of Breast Cancer Therapy

Poverty as a cause and consequence of Ill health

Background and aims: Poverty is a multidimensional phenomenon that can be defined in both economic and social terms. The paper attempts to review the existing evidence to understand the relation between poverty and ill health in the context of the limited conceptual and operational definitions of these terms. The paper uses two of Hills criteria- reversibility and dose response relationship to ...

Hearing loss as an unusual consequence of metastatic gastric adenocarcinoma

A sixty-one year old man was referred with a history of progressive dysphagia, vomiting and weight loss with some back pain. Upper gastrointestinal endoscopy and biopsies revealed a gastro-oesophageal junction adenocarcinoma. Despite the absence of metastatic disease on computed tomography, positron emission tomography demonstrated multiple vertebral and sternal deposits. He was reviewed in an ...

Systemic Targeted Alpha Radiotherapy for Cancer

Background: The fundamental principles of internal targeted alpha therapy for cancer were established many decades ago.The high linear energy transfer (LET) of alpha radiation to the targeted cancer cellscauses double strand breaks in DNA. At the same time, the short range radiation spares adjacent normal tissues. This targeted approach complements conventional external beam radiotherapy and ch...